2009 China-America Frontiers of Engineering Symposium

Engineering and Public Health: Ensuring Food Safety (cont.)

October 19, 2009 11:00 – 12:30
GMOs Analysis in China

To promote the development and safety assessment of genetically modified organisms (GMOs) in China, we characterized the molecular features of more than twenty GMOs in China, and developed the effective approach for analysis of GMOs and their derived products. Totally, five plant-specific endogenous reference genes, LAT52 in tomato (Lycopersicon esculentum), Sad1 in cotton (Gossypium hirsutum), high-mobility-group protein I/Y (HMG-I/Y) in rapeseed (Brassica napus), sucrose phosphate synthase (SPS) in rice, and Chymopapain (CHY) in papaya (Carica papaya L.) were validated and developed for qualitative and quantitative identification of tomato, cotton, rapeseed, rice and papaya respectively. Also tomato Lat52 and rice SPS systems have been validated to be suitable endogenous reference genes for GM tomato and rice detection by international collaborative ring trials.Also 16 methods we developed have been validated at the national levels, and ... More

Implementing Novel Food Technologies by Ensuring the Public Health - A Risk-Based Process Validation Approach

During the design phase of a novel food processing system, the most important task is to consider all of the food safety related concerns and implement the solutions well in advance in the development process. Applying the appropriate tools to determine the risk levels and corresponding control systems is critical for innovative process/product development. 
During the last five years, the Food Industry has slowly shifted to a risk-based approach to regulate their product and process development activities more effectively.  A true meaning of validation has been studied and implemented to integrate more scientifically rigorous quality system, food safety, good engineering practices, qualification and testing methodologies, and risk-management considerations. This new approach put additional emphasis on the true meaning of the validation as a Good Manufacturing Practice beyond just a complicated documentation ... More